What was the most destructive volcanic eruption in the history of the United States?

The May 18, 1980 eruption of Mount St. Helens (Washington) was the most destructive in the history of the United States. Novarupta (Katmai) Volcano in Alaska erupted considerably more material in 1912, but owing to the isolation and sparse population of the region, there were no human deaths and little property damage. In contrast, the eruption of Mount St. Helens caused loss of lives and widespread destruction in a matter of hours.